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Biomedical Photonics

Zhu,Dan

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Zhu,Dan

EDUCATION:

Degree

Start/End Dates

Field of study

Name of organization and department

Ph.D.

1998.9-2001.8

Physical Electronics

Department of Optoelectronics Engineering, HuazhongUniversity of Science Technology (HUST), Wuhan, P.R.China.

M.S.

1989.9-1992.6

Physical Electronics

CentralChina Normal University (CCNU), Wuhan, China.

B.S.

1982.9-1986.6

Physics

HubeiUniversity (HBU), Wuhan, China

 

POSITIONS AND EMPLOYMENT:

Start/end dates

Position Title

Name of organization and department

2007.11-currently

Professor

Wuhannational Laboratory for Optoelectronics

Key Laboratory of Ministry of Education of China

HuazhongUniversity of Science and Technology, Wuhan, China

2009.8-currently

Secretary General

Biomedical Photonics Committee of Chinese Optical Society

2003.6-2007.11

Associate professor

Key Laboratory of Ministry of Education of China, Department of Biomedical Engineering, Huzhong University of Science and Technology, Wuhan, Hubei, China

2005.9-2005.11

Visiting researcher

Department of Optics, Saratov State University, Russia

2001.9-2003.6

Postdoc

Key Laboratory of Ministry of Education of China, Huzhong University of Science and Technology, Wuhan, China

1992.6 ~1998.9

Lecturer

Department of Electric and Electronic Engineering, Wuhan University of Science and Technology, Wuhan, China

1986.6 – 1989.9

Assistant professor

Department of Basic Courses, Hubei Agriculture College, Jingzhou, China

 

PROFESSIONAL ACTIVITIES

Secretary General,Biomedical Photonics Committee of Chinese Optical Society (2009-Currently)

Member of Editorial Board, Guest Editorof Journal of Innovative Optical Health Sciences (JIOHS)

Guest Editor of Photonics & Lasers in Medicine (PLM)

Reviewer of peer-reviewed international journals:Journal of Biomedical Optics, Optics & Lasers in Engineering, Journal of Biophotonics, Biomedical Optics Express, Chinese optical Letters, Frontier of Optoelectronics in China.

Member of SPIE, Advisor of SPIE HUST Chapter.

Member of Program Committeefor Optics in health Care and Biomedical Optics, Photonics Asia 2012, 2010; the 10th, 9th, 8th,7th,6th, 5th, international Conference on Photonics and Imaging in Biology and Medicine (PIBM 2011, 2010, 2009, 2008, 2007, 2006).

Chair of organization committeefor 2011 Annual Conference on Chinese Biomedical Engineering.

She is a holder of almost 100scientific papers, and 2 patents. Since 2005, she has done more than 20 plenary and invited lectures on international or domestic conference.

 

RESEARCH  INTERESTS:

  • Tissue optics theory and technology

  • Tissue optical clearing technology

  • Optical imaging for blood flow or neuroimaging

 

PUBLICATIONS (SELECTED PAPERS )

  1. Jing Wang, Rui Shi, Dan Zhu*,Optical clearing method induced switchable skin window for dermal blood flow imaging,Journal of Biomedical Optics, 18(6), 061209 (2013).

  2. Jing Wang, Rui Shi, Dan Zhu*, Ear skin optical clearing for improving blood flow imaging, Lasers & Photonics in Medicine, 2(1), 2013

  3. Jing Wang,Yang Zhang,Tonghui Xu,Qingming Luo��strong>Dan Zhu*,An innovative transparent cranial window based on skull optical clearing,Laser Physics Letters 9(6), 469-473, 2012

  4. Xiang Wen, Steven L Jacques, Valery V Tuchin, Dan Zhu*,Enhanced optical clearing of skin in vivo and OCT in-depth imaging,Journal of Biomedical Optics, 17(6), 066022, 2012

  5. Tingting Yu,Xiang Wen,Valery V. Tuchin,Qingming Luo��strong>Dan Zhu*,Quantitative analysis of dehydration in porcine skin for assessing mechanism of optical clearing,Journal of Biomedical Optics 16(9), 095002��011

  6. Jing Wang, Dan Zhu*, Preliminary observations of rat skin after topical application of optical clearing agent, Proc. SPIE, 2011, 79999, 79990G, 2011 (invited)

  7. Dan Zhu*, Xiang Wen, Jing Wang, Advances in optical clearing of skin in vivo, SPIE Newsroom, 7, April, 2011 (http://spie.org/x47512.xml?ArticleID=x47512)

  8. Dan Zhu, Jing Wang, Zhongwei Zhi, Xiang Wen, Qingming Luo, Imaging dermal blood flow through the intact rat skin with an optical clearing method, Journal of Biomedical Optics,15(2), 026008, 2010

  9. Caihua Liu, Zhongwei Zhi, Valery V Tuchin, Qingming Luo, Dan Zhu*, Enhancement of skin optical clearing efficacy using photo-irradiation, Lasers in Surgery and Medicine, 42��32��40, 2010

  10. Xiang Wen, Zongzhen Mao, Zhenzhen Han, Valery V Tuchin, Dan Zhu*, In Vivo Skin Optical Clearing by Glycerol Solutions: Mechanism��em>Journal of Biophotonics, 3: 44-52, 2010

  11. Jing Wang,Dan Zhu*, Min Chen And Xiaojing Liu,Assessment of optical clearing induced improvement of laser speckle contrast imaging��em>Journal of Innovative Optical Health Sciences����),159-167��010

  12. Xiang Wen, Valery V Tuchin, Qingming Luo and Dan Zhu*,Control the scattering of Intralipid by using optical clearing agents, Physics in Medicine and Biology, 54��917-6930, 2009

  13. Zhongwei Zhi, Zhenzhen Han, Qingming Luo And Dan Zhu*,Improve optical clearing of skin in vitro with propylene glycol as a penetration enhancer��em>Journal of Innovative Optical Health Sciences����),269-278��009

  14. Sergey Ulyanov, Yulia Ganilova, Dan Zhu, Jianjun Qiu, Pengcheng Li, O. Ulianova and Qingming Luo, LASCA with a small number of scatterers: Application for monitoring of microflow, Europhysics Letters��2 (1),18005, 2008

  15. Dan Zhu, Jing Zhang, Han Cui, Zongzhen Mao, Pengcheng Li, Qingming Luo, Short-term and long-term effects of optical clearing agents on blood vessels in chick chorioallantoic membrane,Journal of Biomedical Optics, 13(2), 2008

  16. Zongzhen Mao, Dan Zhu*, Yating Hu, Xiang Wen, Zhenzhen Han, Qingming Luo, Influence of alcohols on the optical clearing effect of skin in vitro, Journal of Biomedical Optics, 13(2), 2008

  17. Hequn Wang, Gang Lv, Zhenzhi Shi, Dan Zhu*,Study on the pathological uterine tissues with a fiber raman spectrometry,Spectroscopy and Spectral Analysis, 2008

  18. Dan Zhu, Wei Lu, Shaoqun Zeng, Qingming Luo, Effect of light losses of sample between twointegratingspheres on optical properties estimation, Journal of Biomedical Optics, 12(6), 064004, 2007

  19. Dan Zhu, Wei Lu, Yang Weng, Han Cui, Qingming Luo, Monitoring thermal-induced changes in tumor blood flow and microvessels with laser speckle contrast imaging, Applied Optics, 46(10):1911-1917, 2007.

  20. Yong Deng, Shaoqun Zeng, Qiang Lu, Dan Zhu, Qingming Luo,  Characterization of backscattering Mueller matrix patterns of highly scattering media with triple scattering assumption, Optics Express, 15(15): 9672-9680, 2007

  21. Dan Zhu, Qingming Luo, Jian Cen,Effects of dehydration on the optical properties of in vitro porcine liver��em>Laser in surgery and Medicine, 2003��3��26-231

  22. Dan Zhu, Qingming Luo, Guangming Zhu, Wei Liu, Kinetic thermal response and damage in laser coagulation of tissue,Laser Surgery and Medicine, 30(5): 313~321, 2002

  23. Limin Tong, Dan zhu, Qingming Luo, and Defei Hong, A laser pumped Nd3+-doped YAG fiber-optical thermal tip for laser thermotherapy, Lasers in Surgery and Medicine, 30(1): 67~69, 2002

  24. Dan Zhu, Qingming Luo, Jiangsheng Yu, Shaoqun Zeng, Yu RUAN, On thermal kinetics of scattering properties of rat live, J. Asian Physics, 10 (4), 2001

BOOK CHAPTERS

Dan Zhu, Qingming Luo, Valery V Tuchin, “Tissue Optics Clearing”, Advanced Biophotonics: slicing tissue with photons, Valery Tuchin and Ricky Wang, CRC Press. 2013

SPECIAL ISSUES OF JOURNALS

  1. Valery V. Tuchin, Martin Leahy, and Dan Zhu(Guest Editors),Special Issue: Optical Clearing for Biomedical Imaging in the Study of Tissues and Biological Fluids,  J. Innovative Optical Health Sciences, 3(3),2010

  2. Dan Zhu, Valery V Tuchin and Qingming Luo, (Guest Editors), Special Issue: Advances in Biophotonics and Biomedical Optics,  J. Innovative Optical Health Sciences, 6(1), 2013

  3. Dan Zhu, Qingming Luo (Guest Editors), Special Issue: Current Research in China,Photonics & Lasers in Medicine, 2(1), 2013

 

THE MAIN RESEARCH PROJECTS ON GOING OR COMPLETED (2008~):

  1. 2013.1-2015.12: A stable cranial window with optical clearing method for transcranial cortical optical neuroimaging in vivo,PI-Dan Zhu(National Nature Science Foundation of China, Grant No. 91232710),

  2. 2012.1-2015.12: Mechanisms of optical clearing of tissue in vivo,PI-Dan Zhu (National Nature Science Foundation of China, Grant No. 81171376),

  3. 2012.1-2014.12: Mechanisms of optical clearing of tissue in vivo with molecular dynamics and hyperspectral imaging,PI-Dan Zhu (Research Fund for the Doctoral Program of Higher Education of China (No. 20110142110073),

  4. 2009.1-2010.12: Physical and physiological mechanisms of skin optical clearing, PI-Dan Zhu (NSFC-RFBR for International Cooperation, Grant No.30911120074),

  5. 2008.1-2010.12: The Effect of Optical Clearing Agents on Blood Vessels with Optical Imaging Techniques,PI-Dan Zhu(National Nature Science Foundation of China, Grant No. 30770552),

  6. 2010.1-2011.12: Innovative techniques and methods for improving phototherapy effect of skin disease, PI-Dan Zhu(Chinese/Russian Government Cooperation Project, Grant No. 13-26)


Research Areas

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Awards and Honors

Professional Activities

Research & Faculty